Born in Beirut, Pamela Ghanime graduated from the film school at the Institut d’études scéniques, audiovisuelles et cinématographiques (IESAV) in Lebanon. She has written and directed two medium length documentaries: Yom min omri (2002) and Lemon Flowers (2007). She served as the director of photography and editor of several documentaries directed by Mohamad Soueid, including Civil War (2002), My Heart Beats Only for Her (2008), The Sky is not Always Above (2006), How Bitter my Sweet (2010), A Spell of Absence (2011).

She edited Homo Politicus, a full-length documentary directed by Henri Poulain; Of heroes, Football and all that remains from my childhood (2011), a video installation by Lynn Kodeih; Ebn el Amm online (2001), a documentary directed by Ali Atassi; A Big Red Heart (2022) and Beirut Hold’em (2022), two feature films directed by Michel Kammoun.

She has also worked on the editing of the feature length documentary The Tents (2002) directed by Dalia Fathallah and directed the podcast series Khido Nafas (2022). She also edited The Tree of Hell (2024), a documentary film directed by Raed Zeno.